SPP 2330

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Publications

2024

  • Kohm K, v. Clanner A, Hertel R, Commichau FM (2024) Closely related and yet special – how SPβ family phages control lysis-lysogeny decisions. Trends Microbiol https://doi.org/10.1016/j.tim.2024.11.007
  • Wegner, H., Roitman, S., Kupczok, A. et al. Identification of Shemin pathway genes for tetrapyrrole biosynthesis in bacteriophage sequences from aquatic environments. Nat Commun 15, 8783 (2024). https://doi.org/10.1038/s41467-024-52726-3
  • Pozhydaieva, N., Billau, F. A., Wolfram-Schauerte, M., Ramírez Rojas, A. A., Paczia, N., Schindler, D., & Höfer, K. (2024). Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications. PLoS genetics, 20(9), e1011384.
  • Cortés-Martín A, Buttimer C, Pozhydaieva N, Hille F, Shareefdeen H, Bolocan AS, Draper LA, Shkoporov AN, Franz CMAP, Höfer K, Ross RP, Hill C. Isolation and characterization of Septuagintavirus; a novel clade of Escherichia coli phages within the subfamily Vequintavirinae. Microbiol Spectr. 2024 Sep 3;12(9):e0059224. doi: 10.1128/spectrum.00592-24.
  • Wolfram-Schauerte, M., Moskalchuk, A., Pozhydaieva, N., Rojas, A. A. R., Schindler, D., Kaiser, S., … & Höfer, K. (2024). T4 phage RNA is NAD-capped and alters the NAD-cap epitranscriptome of Escherichia coli during infection through a phage-encoded decapping enzyme. bioRxiv, 2024-04.
  • Pozhydaieva, N., Höfer, K. (2024). Utilizing Golden Gate assembly to streamline CRISPR-Cas/NgTET-based phage mutagenesis (in print in Methods in Molecular Biology, DOI : 10.1007/978-1-0716-4094-4)
  • Béchon N, Tal N, Stokar-Avihail A, Melamed S, Amitai G, Sorek R (2024) Diversification of molecular pattern recognition in bacterial NLR-like proteins. bioRxiv:2024.2001.2031.578182, doi:10.1101/2024.01.31.578182
  • Beck C, Krusche J, Elsherbini AMA, Du X, Peschel A (2024) Phage susceptibility determinants of the opportunistic pathogen Staphylococcus epidermidis. Curr Opin Microbiol, 78:102434, doi:10.1016/j.mib.2024.102434 3
  • Beck C, Krusche J, Notaro A, Walter A, Kränkel L, Vollert A, Stemmler R, Wittmann J, Schaller M, Slavetinsky C, Mayer C, Castro CD, Peschel A (2024) Wall teichoic acid substitution with glucose governs phage susceptibility of Staphylococcus epidermidis. mBio, In press doi:10.1101/2023.07.27.550822
  • d. H. Almási É, Knischewski N, Osbelt L, Muthukumarasamy U, El Mouali Y, Vialetto E, Beisel CL, Strowig T (2024) An adapted method for Cas9-mediated editing reveals the species-specific role of β-glucoside utilization driving competition between Klebsiella species. Journal of Bacteriology, 0 (0):e00317-00323, doi:10.1128/jb.00317-23
  • Erdrich SH, Luthe T, Kever L, Roigé BB, Arsova B, Davoudi E, Frunzke J (2024) Expanding the phage galaxy: Isolation and characterization of five novel Streptomyces siphoviruses Ankus, Byblos, DekoNeimoidia, Mandalore, and Naboo. bioRxiv:2024.2002.2016.580700, doi:10.1101/2024.02.16.580700
  • Gerovac M, Chihara K, Wicke L, Böttcher B, Lavigne R, Vogel J (2024) Phage proteins target and co-opt host ribosomes immediately upon infection. Nature Microbiology, accepted, doi:10.1101/2023.02.26.530069
  • Kever L, Zhang Q, Hardy A, Westhoff P, Yu Y, Frunzke J (2024) Decoupling the molecular versatility of aminoglycosides via drug or target modification enables community-wide antiphage defense. bioRxiv:2024.2002.2027.582341, doi:10.1101/2024.02.27.582341
  • Krusche J, Beck C, Lehmann E, Gerlach D, Wolz C, Peschel A (2024) Systematic mapping of phage receptor-binding proteins predicts surface glycopolymer structure in Staphylococcus pathogens. To be submitted to BioRxiv
  • Kuiper BP, Schöntag AMC, Oksanen HM, Daum B, Quax TEF (2024) Archaeal virus entry and egress. Microlife, 5:uqad048, doi:10.1093/femsml/uqad048
  • Maier L, Stein-Thoeringer C, Ley R, Brötz-Oesterhelt H, Link H, Ziemert N, Wagner S, Peschel A (2024) Integrating research on bacterial pathogens and commensals to fight infections – an ecological perspective. Lancet Microbe In press
  • Osterman I, Samra H, Rousset F, Loseva E, Itkin M, Malitsky S, Yirmiya E, Millman A, Sorek R (2024) Phages reconstitute NAD+ to counter bacterial immunity. bioRxiv:2024.2002.2011.579819, doi:10.1101/2024.02.11.579819
  • Pozhydaieva N, Wolfram-Schauerte M, Keuthen H, Höfer K (2024) The enigmatic epitranscriptome of bacteriophages: putative RNA modifications in viral infections. Curr Opin Microbiol, 77:102417, doi:10.1016/j.mib.2023.102417
  • Putzeys L, Wicke L, Boon M, van Noort V, Vogel J, Lavigne R (2024) Refining the transcriptional landscapes for distinct clades of virulent phages infecting Pseudomonas aeruginosa. μLife, accepted, doi: 10.1101/2023.10.13.562163
  • Putzeys L, Wicke L, Brandão A, Boon M, Pires DP, Azeredo J, Vogel J, Lavigne R, Gerovac M (2024) Exploring the transcriptional landscape of phage-host interactions using novel high-throughput approaches. Curr Opin Microbiol, 77:102419, doi:10.1016/j.mib.2023.102419
  • Rackow B, Rolland C, Mohnen I, Wittmann J, Müsken M, Overmann J, Frunzke J (2024) Isolation and characterization of the new Streptomyces phages Kamino, Geonosis, Abafar and Scarif infecting a broad range of host species. bioRxiv:2024.2002.2026.582091, doi:10.1101/2024.02.26.582091
  • Thiele Orberg E, Meedt E, Hiergeist A, Xue J, Heinrich P, Ru J, Ghimire S, Miltiadous O, Lindner S, Tiefgraber M, Göldel S, Eismann T, Schwarz A, Göttert S, Jarosch S, Steiger K, Schulz C, Gigl M, Fischer JC, Janssen KP, Quante M, Heidegger S, Herhaus P, Verbeek M, Ruland J, van den Brink MRM, Weber D, Edinger M, Wolff D, Busch DH, Kleigrewe K, Herr W, Bassermann F, Gessner A, Deng L, Holler E, Poeck H (2024) Bacteria and bacteriophage consortia are associated with protective intestinal metabolites in patients receiving stem cell transplantation. Nat Cancer, 5 (1):187-208, doi:10.1038/s43018-023-00669-x
  • Thöneböhn S, Fischer D, Kreiling V, Kemmler A, Oberheim I, Hager F, Schmid N, E. , Thormann K, M. (2024) Identifying the components of the Shewanella phage LambdaSo lysis system. bioRxiv:2024.2001.2023.576932, doi:10.1101/2024.01.23.576932
  • Wimmer F, Englert F, Wandera KG, Alkhnbashi OS, Collins SP, Backofen R, Beisel CL (2024) Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA degradation. Nucleic Acids Res, 52 (2):769-783, doi:10.1093/nar/gkad1097
  • Yirmiya E, Leavitt A, Lu A, Ragucci AE, Avraham C, Osterman I, Garb J, Antine SP, Mooney SE, Hobbs SJ, Kranzusch PJ, Amitai G, Sorek R (2024) Phages overcome bacterial immunity via diverse anti-defence proteins. Nature, 625 (7994):352-359, doi:10.1038/s41586-023-06869-w

2023

  • Gehlert FO, Weidenbach K, Barüske B, Hallack D, Repnik U, Schmitz RA (2023) Newly Established Genetic System for Functional Analysis of MetSV. Int J Mol Sci, 24 (13) doi:10.3390/ijms241311163
  • Gomes-Filho JV, Breuer R, Morales-Filloy HG, Pozhydaieva N, Borst A, Paczia N, Soppa J, Höfer K, Jäschke A, Randau L (2023) Identification of NAD-RNA species and ADPR-RNA decapping in Archaea. Nat Commun, 14 (1):7597, doi:10.1038/s41467-023-43377-x
  • Gratani FL, Englert T, Nashier P, Sass P, Czech L, Neumann N, Doello S, Mann P, Blobelt R, Alberti S, Forchhammer K, Bange G, Höfer K, Macek B (2023) E. coli Toxin YjjJ (HipH) Is a Ser/Thr Protein Kinase That Impacts Cell Division, Carbon Metabolism, and Ribosome Assembly. mSystems, 8 (1):e0104322, doi:10.1128/msystems.01043-22
  • Guo Y, Du X, Krusche J, Beck C, Ali S, Walter A, Winstel V, Mayer C, Codée JDC, Peschel A, Stehle T (2023) Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition. Sci Adv, 9 (47):eadj2641, doi:10.1126/sciadv.adj2641
  • Hardy A, Kever L, Frunzke J (2023) Antiphage small molecules produced by bacteria – beyond protein-mediated defenses. Trends Microbiol, 31 (1):92-106, doi:10.1016/j.tim.2022.08.001
  • Hochhauser D, Millman A, Sorek R (2023) The defense island repertoire of the Escherichia coli pan-genome. PLoS Genet, 19 (4):e1010694, doi:10.1371/journal.pgen.1010694
  • Jakob MO, Spari D, Sànchez Taltavull D, Salm L, Yilmaz B, Doucet Ladevèze R, Mooser C, Pereyra D, Ouyang Y, Schmidt T, Mattiola I, Starlinger P, Stroka D, Tschan F, Candinas D, Gasteiger G, Klose CSN, Diefenbach A, Gomez de Agüero M, Beldi G (2023) ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery. Cell Rep, 42 (3):112269, doi:10.1016/j.celrep.2023.112269
  • Jiao C, Reckstadt C, König F, Homberger C, Yu J, Vogel J, Westermann AJ, Sharma CM, Beisel CL (2023) RNA recording in single bacterial cells using reprogrammed tracrRNAs. Nat Biotechnol, 41 (8):1107-1116, doi:10.1038/s41587-022-01604-8
  • Kohm K, Jalomo-Khayrova E, Krüger A, Basu S, Steinchen W, Bange G, Frunzke J, Hertel R, Commichau FM, Czech L (2023) Structural and functional characterization of MrpR, the master repressor of the Bacillus subtilis prophage SPβ. Nucleic Acids Res, 51 (17):9452-9474, doi:10.1093/nar/gkad675
  • Lai LB, Gopalan V, Jansson MD, Chen Q, Zhang X, Wolfram-Schauerte M, Höfer K (2023) Making nucleic acid structures and schematics. Trends Biochem Sci, 48 (8):655-658, doi:10.1016/j.tibs.2023.05.005
  • Lehmann E, Dalen Rv, Gritsch L, Slavetinsky C, Korn N, Rohmer C, Krause D, Peschel A, Weidenmaier C, Wolz C (2023) The capsular polysaccharide obstructs wall teichoic acid functions in Staphylococcus aureus. bioRxiv:2023.2007.2026.550747, doi:10.1101/2023.07.26.550747
  • Luthe T, Kever L, Hänsch S, Hardy A, Tschowri N, Weidtkamp-Peters S, Frunzke J (2023) Streptomyces development is involved in the efficient containment of viral infections. Microlife, 4:uqad002, doi:10.1093/femsml/uqad002
  • Luthe T, Kever L, Thormann K, Frunzke J (2023) Bacterial multicellular behavior in antiviral defense. Curr Opin Microbiol, 74:102314, doi:10.1016/j.mib.2023.102314
  • Papenfort K, Melamed S (2023) Small RNAs, Large Networks: Posttranscriptional Regulons in Gram-Negative Bacteria. Annu Rev Microbiol, 77:23-43, doi:10.1146/annurev-micro-041320-025836
  • Rousset F, Sorek R (2023) The evolutionary success of regulated cell death in bacterial immunity. Curr Opin Microbiol, 74:102312, doi:10.1016/j.mib.2023.102312
  • Rousset F, Yirmiya E, Nesher S, Brandis A, Mehlman T, Itkin M, Malitsky S, Millman A, Melamed S, Sorek R (2023) A conserved family of immune effectors cleaves cellular ATP upon viral infection. Cell, 186 (17):3619-3631.e3613, doi:10.1016/j.cell.2023.07.020
  • Schmid N, E., Brandt D, Walasek C, Rolland C, Wittmann J, Müsken M, Kalinowski J, Thormann K, M. (2023) A rolling circle-replicating plasmid as an Inovirus phage satellite. bioRxiv:2023.2011.2028.569023, doi:10.1101/2023.11.28.569023
  • Slavetinsky J, Lehmann E, Slavetinsky C, Gritsch L, van Dalen R, Kretschmer D, Bleul L, Wolz C, Weidenmaier C, Peschel A (2023) Wall Teichoic Acid Mediates Staphylococcus aureus Binding to Endothelial Cells via the Scavenger Receptor LOX-1. ACS Infect Dis, 9 (11):2133-2140, doi:10.1021/acsinfecdis.3c00252
  • Sprenger M, Siemers M, Krautwurst S, Papenfort K (2023) Small Rnas Direct Attack and Defence Mechanisms in a Quorum Sensing Phage and its Host. SSRN Preprint:http://dx.doi.org/10.2139/ssrn.4650796 doi:http://dx.doi.org/10.2139/ssrn.4650796
  • Stante M, Weiland-Bräuer N, Repnik U, Werner A, Bramkamp M, Chibani CM, Schmitz RA (2023) Four Novel Caudoviricetes Bacteriophages Isolated from Baltic Sea Water Infect Colonizers of Aurelia aurita. Viruses, 15 (7) doi:10.3390/v15071525
  • Stokar-Avihail A, Fedorenko T, Hör J, Garb J, Leavitt A, Millman A, Shulman G, Wojtania N, Melamed S, Amitai G, Sorek R (2023) Discovery of phage determinants that confer sensitivity to bacterial immune systems. Cell, 186 (9):1863-1876.e1816, doi:10.1016/j.cell.2023.02.029
  • Sun J, Ru J, Ramos-Mucci L, Qi F, Chen Z, Chen S, Cribbs AP, Deng L, Wang X (2023) DeepsmirUD: Prediction of Regulatory Effects on microRNA Expression Mediated by Small Molecules Using Deep Learning. Int J Mol Sci, 24 (3) doi:10.3390/ijms24031878
  • Unterer M, Khan Mirzaei M, Deng L (2023) Targeted Single-Phage Isolation Reveals Phage-Dependent Heterogeneous Infection Dynamics. Microbiol Spectr, 11 (3):e0514922, doi:10.1128/spectrum.05149-22
  • Vento JM, Durmusoglu D, Li T, Sullivan S, Ttofali F, van Schaik J, Yu Y, Barquist L, Crook N, Beisel CL (2023) A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria. bioRxiv:2023.2009.2016.557782, doi:10.1101/2023.09.16.557782
  • Vogel J, de Lorenzo V (2023) EAM highlights in FEMS 2023: from the Petri dish to planet Earth. Microlife, 4:uqad045, doi:10.1093/femsml/uqad045
  • von Strempel A, Weiss AS, Wittmann J, Salvado Silva M, Ring D, Wortmann E, Clavel T, Debarbieux L, Kleigrewe K, Stecher B (2023) Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice. PLoS Pathog, 19 (8):e1011600, doi:10.1371/journal.ppat.1011600
  • Wegner H, Roitman S, Kupczok A, Braun V, Woodhouse J, Grossart H-P, Beja O, Zehner S, Frankenberg-Dinkel N (2023) Virus-encoded Shemin pathway highlights the importance of tetrapyrrole metabolism during host infection. bioRxiv:2023.2012.2011.571061, doi:10.1101/2023.12.11.571061
  • Wolfram-Schauerte M, Höfer K (2023) NAD-capped RNAs – a redox cofactor meets RNA. Trends Biochem Sci, 48 (2):142-155, doi:10.1016/j.tibs.2022.08.004
  • Wolfram-Schauerte M, Pozhydaieva N, Grawenhoff J, Welp LM, Silbern I, Wulf A, Billau FA, Glatter T, Urlaub H, Jäschke A, Höfer K (2023) A viral ADP-ribosyltransferase attaches RNA chains to host proteins. Nature, 620 (7976):1054-1062, doi:10.1038/s41586-023-06429-2
  • Wolfram-Schauerte M, Pozhydaieva N, Höfer K (2023) Molekulare Schnappschüsse der Phageninfektion. Biospektrum, 29:257–261, doi:https://doi.org/10.1007/s12268-023-1923-x
  • Yang J, Bowring JZ, Krusche J, Lehmann E, Bejder BS, Silva SF, Bojer MS, Grunert T, Peschel A, Ingmer H (2023) Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus. Cell Rep, 42 (9):113154, doi:10.1016/j.celrep.2023.113154
  • Yousefi MH, Wagemans J, Shekarforoush SS, Vallino M, Pozhydaieva N, Höfer K, Lavigne R, Hosseinzadeh S (2023) Isolation and molecular characterization of the Salmonella Typhimurium orphan phage Arash. BMC Microbiol, 23 (1):297, doi:10.1186/s12866-023-03056-9
Patents:
  • Erdrich S, Arsova B, Frunzke J, Schurr U (2023) Matrix-vermittelte Beschichtung von Zielorganismen mit Bioeffektoren. Patentanmeldung in Deutschland Nr. 102023123382.3 (Ihr Az.: PT 0.3392/pa MB Az.: D/FZJDUE-058-DE)
  • Höfer K, Wolfram Schauerte M (2023) ((2923), NudE.1, European Patent Application, No. 24 157 075.3
  • Höfer K, Pozhydaieva N (2023), Engineering of Phages, European Patent Application /
    No. 23 175 257.7

2022

  • Aguirre Sourrouille Z, Schwarzer S, Lequime S, Oksanen HM, Quax TEF (2022) The Viral Susceptibility of the Haloferax Species. Viruses, 14 (6) doi: 10.3390/v14061344
  • Chibani CM, Mahnert A, Borrel G, Almeida A, Werner A, Brugère JF, Gribaldo S, Finn RD, Schmitz RA, Moissl-Eichinger C (2022) A catalogue of 1,167 genomes from the human gut archaeome. Nat Microbiol, 7 (1):48-61, doi:10.1038/s41564-021-01020-9
  • Garb J, Lopatina A, Bernheim A, Zaremba M, Siksnys V, Melamed S, Leavitt A, Millman A, Amitai G, Sorek R (2022) Multiple phage resistance systems inhibit infection via SIR2-dependent NAD(+) depletion. Nat Microbiol, 7 (11):1849-1856, doi:10.1038/s41564-022-01207-8
  • Gehlert FO, Sauerwein T, Weidenbach K, Repnik U, Hallack D, Förstner KU, Schmitz RA (2022) Dual-RNAseq Analysis Unravels Virus-Host Interactions of MetSV and Methanosarcina mazei. Viruses, 14 (11) doi:10.3390/v14112585
  • Gerlach D, Sieber RN, Larsen J, Krusche J, De Castro C, Baumann J, Molinaro A, Peschel A (2022) Horizontal transfer and phylogenetic distribution of the immune evasion factor tarP. Front Microbiol, 13:951333, doi:10.3389/fmicb.2022.951333
  • Gomez de Agüero M, Rahimi-Midani A (2022) Don’t forget the bacteriophages. Lab Anim (NY), 51 (6):160-161, doi:10.1038/s41684-022-00986-1
  • Gomez-Raya-Vilanova MV, Leskinen K, Bhattacharjee A, Virta P, Rosenqvist P, Smith JLR, Bayfield OW, Homberger C, Kerrinnes T, Vogel J, Pajunen MI, Skurnik M (2022) The DNA polymerase of bacteriophage YerA41 replicates its T-modified DNA in a primer-independent manner. Nucleic Acids Res, 50 (7):3985-3997, doi:10.1093/nar/gkac203
  • Hinrichs R, Pozhydaieva N, Höfer K, Graumann PL (2022) Y-Complex Proteins Show RNA-Dependent Binding Events at the Cell Membrane and Distinct Single-Molecule Dynamics. Cells, 11 (6) doi:10.3390/cells11060933
  • Hobbs SJ, Wein T, Lu A, Morehouse BR, Schnabel J, Leavitt A, Yirmiya E, Sorek R, Kranzusch PJ (2022) Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. Nature, 605 (7910):522-526, doi:10.1038/s41586-022-04716-y
  • Kever L, Hardy A, Luthe T, Hünnefeld M, Gätgens C, Milke L, Wiechert J, Wittmann J, Moraru C, Marienhagen J, Frunzke J (2022) Aminoglycoside Antibiotics Inhibit Phage Infection by Blocking an Early Step of the Infection Cycle. mBio, 13 (3):e0078322, doi:10.1128/mbio.00783-22
  • Leavitt A, Yirmiya E, Amitai G, Lu A, Garb J, Herbst E, Morehouse BR, Hobbs SJ, Antine SP, Sun ZJ, Kranzusch PJ, Sorek R (2022) Viruses inhibit TIR gcADPR signalling to overcome bacterial defence. Nature, 611 (7935):326-331, doi:10.1038/s41586-022-05375-9
  • Monsees I, Turzynski V, Esser SP, Soares A, Timmermann LI, Weidenbach K, Banas J, Kloster M, Beszteri B, Schmitz RA, Probst AJ (2022) Label-Free Raman Microspectroscopy for Identifying Prokaryotic Virocells. mSystems, 7 (1):e0150521, doi:10.1128/msystems.01505-21
  • Petrov DP, Kaiser S, Kaiser S, Jung K (2022) Opportunities and Challenges to Profile mRNA Modifications in Escherichia coli. Chembiochem, 23 (18):e202200270, doi:10.1002/cbic.202200270
  • Rohmer C, Dobritz R, Tuncbilek-Dere D, Lehmann E, Gerlach D, George SE, Bae T, Nieselt K, Wolz C (2022) Influence of Staphylococcus aureus Strain Background on Sa3int Phage Life Cycle Switches. Viruses, 14 (11) doi:10.3390/v14112471
  • Tal N, Millman A, Stokar-Avihail A, Fedorenko T, Leavitt A, Melamed S, Yirmiya E, Avraham C, Brandis A, Mehlman T, Amitai G, Sorek R (2022) Bacteria deplete deoxynucleotides to defend against bacteriophage infection. Nat Microbiol, 7 (8):1200-1209, doi:10.1038/s41564-022-01158-0
  • Venturini C, Petrovic Fabijan A, Fajardo Lubian A, Barbirz S, Iredell J (2022) Biological foundations of successful bacteriophage therapy. EMBO Mol Med, 14 (7):e12435, doi:10.15252/emmm.202012435
  • Wein T, Sorek R (2022) Bacterial origins of human cell-autonomous innate immune mechanisms. Nat Rev Immunol, 22 (10):629-638, doi:10.1038/s41577-022-00705-4
  • Wolfram-Schauerte M, Pozhydaieva N, Viering M, Glatter T, Höfer K (2022) Integrated Omics Reveal Time-Resolved Insights into T4 Phage Infection of E. coli on Proteome and Transcriptome Levels. Viruses, 14 (11) doi:10.3390/v14112502

2021

  • Bange G, Brodersen DE, Liuzzi A, Steinchen W (2021) Two P or Not Two P: Understanding Regulation by the Bacterial Second Messengers (p)ppGpp. Annu Rev Microbiol, 75:383-406, doi:10.1146/annurev-micro-042621-122343
  • Du X, Larsen J, Li M, Walter A, Slavetinsky C, Both A, Sanchez Carballo PM, Stegger M, Lehmann E, Liu Y, Liu J, Slavetinsky J, Duda KA, Krismer B, Heilbronner S, Weidenmaier C, Mayer C, Rohde H, Winstel V, Peschel A (2021) Staphylococcus epidermidis clones express Staphylococcus aureus-type wall teichoic acid to shift from a commensal to pathogen lifestyle. Nat Microbiol, 6 (6):757-768, doi:10.1038/s41564-021-00913-z
  • Fišarová L, Botka T, Du X, Mašlaňová I, Bárdy P, Pantůček R, Benešík M, Roudnický P, Winstel V, Larsen J, Rosenstein R, Peschel A, Doškař J (2021) Staphylococcus epidermidis Phages Transduce Antimicrobial Resistance Plasmids and Mobilize Chromosomal Islands. mSphere, 6 (3) doi: 10.1128/mSphere.00223-21
  • Irmscher T, Roske Y, Gayk I, Dunsing V, Chiantia S, Heinemann U, Barbirz S (2021) Pantoea stewartii WceF is a glycan biofilm-modifying enzyme with a bacteriophage tailspike-like fold. J Biol Chem, 296:100286, doi:10.1016/j.jbc.2021.100286
  • Tal N, Morehouse BR, Millman A, Stokar-Avihail A, Avraham C, Fedorenko T, Yirmiya E, Herbst E, Brandis A, Mehlman T, Oppenheimer-Shaanan Y, Keszei AFA, Shao S, Amitai G, Kranzusch PJ, Sorek R (2021) Cyclic CMP and cyclic UMP mediate bacterial immunity against phages. Cell, 184 (23):5728-5739.e5716, doi:10.1016/j.cell.2021.09.031
  • Wolfram-Schauerte M, Pozhydaieva N, Höfer K (2021) Shaping the Bacterial Epitranscriptome-5′-Terminal and Internal RNA Modifications. Adv Biol (Weinh), 5 (8):e2100834, doi:10.1002/adbi.202100834
  • Weidenbach K, Wolf S, Kupczok A, Kern T, Fischer MA, Reetz J, Urbańska N, Künzel S, Schmitz RA, Rother M (2021) Characterization of Blf4, an Archaeal Lytic Virus Targeting a Member of the Methanomicrobiales. Viruses, doi: 10.3390/v13101934
Patents:
  • Kever L, Frunzke J (2021) Protein-basierter Wachstumsinhibitor in Bakterien“ PT 1.2939
  • Höfer K, Jäschke A (2021), RNAylation-tag, international patent application No. PCT/EP2021/071295

Preliminary Results

  • Höfer K*, Schauerte M, Grawenhoff J, Wulf A, Welp LM, Billau FA, Urlaub H, Jäschke A* (2021) Viral ADP-ribosyltransferases attach RNA chains to host proteins. bioRxiv, doi: https://doi.org/10.1101/2021.06.04.446905
  • Schauerte M, Pozhydaieva N, Höfer K* (2021) Shaping the Bacterial Epitranscriptome—5′-Terminal and Internal RNA Modifications. Advanced Biology, doi: https://doi.org/10.1002/adbi.202100834
  • Tittes C, Schwarzer S, Pfeiffer F, Dyall-Smith M, Rodriguez-Franco M, Oksanen H.M., Quax T.E.F. *(2021) Cellular and genomic properties of Haloferax gibbonsii LR2-5, the host of euryarchaeal virus HFTV1. Frontiers in Microbiology, 16;12:625599.
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